Chemical & Pharmaceutical Cylinder Filter and Dryer
In the production process of the drug substance, after the material crystallizes, in order to reduce the material loss and pollution that the material may cause during the transfer process and damage the environment, the subsequent material filtering, washing and drying processes are usually concentrated in one main body of the equipment. The device is referred to as a "three-in-one" device. The most common type of "three-in-one" equipment used in pharmaceutical production is flat-bottomed, which has certain advantages in the production of sterile bulk drugs. However, the "three-in-one" equipment in the flat-bottom form still has certain defects, such as: small round flat-bottom filtering area; side discharge, which results in incomplete discharge; the drying effect is not ideal, the material turnover during the drying process is small, and heat exchange Low efficiency, limited drying effect, etc.
The development of the cone-shaped filter washing and drying "three-in-one" equipment (hereinafter referred to as the cone-three-in-one) was started around 1993. Based on a comprehensive analysis of the advantages and disadvantages of domestic "three-in-one" equipment, Wuxi Shuangrui Machinery Co., Ltd. has learned from its strengths and weaknesses. After five generations of development and upgrading, it has developed into a current clean application-grade model, which has been successfully used in the production of bulk drugs for more than 10 years.
Chemical & Pharmaceutical Cylinder Filter and Dryer Working principle
Before feeding the stirrer filter or filter dryer, nitrogen is injected into the container to exhaust the oxygen inside. This step can prevent the potentially explosive environment inside the container.
After the purification is completed, the filtrate is poured into a container.
The filtrate is pushed into the inside of the container by nitrogen, and extends from under the filter cloth. The solid is left on the filter cloth, and the mother liquor flows through the shaped filter cake.
After the filtrate is separated from the filter cake, the cleaning process is started.
Before replacement washing, smooth the filter cake surface with a stirrer to prevent the cake from cracking.
Use a cleaning ring with a nozzle to evenly distribute the washing liquid over the entire cake surface. By pressurizing the inside of the container again, the washing liquid is washed through the filter cake to replace the remaining mother liquor, and the mother liquor in the filtration is discharged by the same method.
In the re-beating process, the cleaning solution is added to the container and mixed with the materials and stirred. By pressurizing the inside of the container again, the washing liquid is washed through the filter cake to replace the remaining mother liquor, and the mother liquor in the filtration is discharged by the same method.
After washing, the drying process begins. In order to achieve a good drying effect, the vacuum drying and heating of the filter dryer are performed simultaneously. During the drying process, the materials are constantly stirred. The filter dryer maintains the vacuum and constant temperature (allowable temperature of the material) until the humidity of the material reaches the demand.
After the drying process is finished, the product is cooled and then discharged.
The dried and cooled product is removed from the discharge valve on the side. The product is sent to the discharge valve by the stirring arm.
Use a spray ball to spray the cleaning solution on the product contact surface, and perform internal cleaning of the container environment between each production batch or when the product is exchanged. This step enables sufficient and efficient cleaning of the inside of the dryer.
Chemical & Pharmaceutical Cylinder Filter and Dryer Advantages:
1. One machine is multi-purpose, which can complete reactions, extraction, filtration, repeated filtering and washing, drying and other operations in one machine, and directly obtain the finished product.
2. Closed operation, especially suitable for handling flammable, explosive, toxic or highly toxic dangerous products, and delicious foods, biological products and medicines that are not allowed to be contaminated.
3. The body jacket, cone jacket, hollow shaft and hollow ribbon can heat or cool materials at the same time, with high thermal efficiency and low energy consumption.
4.Special mixing screw design can make the material be stirred evenly in the various stages of reaction, filtration, washing and drying, so that the work efficiency of the whole machine is very high.
5. In the filtering stage, due to the good adhesion of the spiral ribbon and the filter medium, the material can be filtered under the condition of a thin layer of filter cake, and the filtering efficiency is high.
6. Simplify and shorten the process flow, occupy a small area, and greatly save investment in plant and equipment.
7. Easy operation, low labor intensity and good quality of processed products.
Simulation of barrel cone “three-in-one” material turning effect
Customer Case Show